Kolkata, July 09: Kerala health Minister Veena George confirmed the first case of Zika virus and there are 13 other suspected cases of the virus from Thiruvananthapuram.
A 24-year-old woman, hailing from Parassala in Thiruvananthapuram district, was hospitalized on 28 June with fever, headache, and red marks on her body. The tests conducted at the hospital confirmed that she was positive following which her samples were sent to NIV, Pune.
The woman, who is undergoing treatment at a private hospital in Thiruvananthapuram, delivered her baby on 7 July and her condition was satisfactory.
Though she does not have any travel history outside the state, her house is on the Tamil Nadu border and a week ago, her mother had also shown similar symptoms, a government release added.
Zika virus infection:
The Zika virus is transmitted by the Aedes mosquito, and the symptoms are similar to dengue including fever, skin rashes, and joint pain. According to the World Health Organisation (WHO), the symptoms, which are generally mild and also include conjunctivitis, muscle pain, malaise, and headache, usually last for 2–7 days. The majority of those infected with the Zika virus do not develop symptoms.
According to the Centre for Disease Control (CDC), severe diseases requiring hospitalization and deaths are uncommon. However, in rare cases, Zika may cause Guillain-Barré syndrome (GBS).
What is Guillain-Barré syndrome?
According to the CDC, Guillain-Barré syndrome is “an uncommon sickness of the nervous system in which a person’s own immune system damages the nerve cells, causing muscle weakness, and sometimes, paralysis.”
The WHO states that the syndrome can affect the peripheral nerves that control muscle strength as well as those transmitting feelings of pain, temperature, and touch, which can result in muscle weakness and loss of sensation in the legs and/or arms.
What are the causes?
According to the CDC, the causes of GBS are not yet fully known but in most cases, GBS is preceded by an infection. This could be a bacterial or viral infection, according to the WHO. GBS may also be triggered by vaccine administration or surgery, it adds.
According to the National Institute of Neurological Disorders and Strokein the US’s National Institutes of Health, GBS is neither contagious nor hereditary. It is called an autoimmune disease as the damage is caused by the body’s own immune system.
“Normally the immune system uses antibodies (molecules produced in an immune response) and special white blood cells to protect us by attacking infecting microorganisms (bacteria and viruses). In Guillain-Barré syndrome, however, the immune system mistakenly attacks the healthy nerves,” it states.
How is GBS associated with the Zika virus?
In several countries where Zika virus outbreaks have been reported, an increase in GBS cases has been observed. The CDC states that its research suggests that GBS is strongly associated with Zika but only a small proportion of people with recent Zika virus infection get GBS.
Does the syndrome affect a particular age group more?
According to the NINDS, GBS is estimated to affect about one in 1,00,000 people each year. According to the WHO, Guillain-Barré is a rare condition. Although it is more common in adults and in males, it can affect people in all age groups. The CDC states that true “clusters” of GBS cases are very unusual.
What are the symptoms?
The WHO lists the following symptoms for the Guillain-Barré syndrome:
- The first symptoms include weakness or tingling sensation, which usually start in the legs, and can spread to the arms and face.
- For some people, these symptoms can lead to paralysis of the legs, arms, or muscles in the face.
- In 20 to 30 percent of cases, the chest muscles are affected, making it hard to breathe.
- In severe cases, the ability to speak and swallow may become affected. These cases are considered life-threatening, and affected individuals should be treated in intensive-care units.
- Complications can include paralysis of the muscles that control breathing, blood infection, lung clots, or cardiac arrest, and even in the best of settings, 3–5 percent of patients suffering from the syndrome die from the complications.
- The NINDS also lists difficulty with eye muscles and vision, coordination problems and unsteadiness, pain that can be severe, particularly at night, abnormal heartbeat/rate or blood pressure, and problems with digestion and/or bladder control as probable symptoms. It states that most people seek medical care following weakness on both sides of the body.
- Occasionally symptoms start in the upper body and move down to the legs and feet, the NINDS adds.
- The global health body states that the symptoms typically last a few weeks but most people most recover fully from even the most severe case of Guillain-Barré syndrome. While some continue to experience weakness, most recover without long-term, severe neurological complications.
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What treatment does it require?
There is no known cure for GBS but there are treatments that can help improve symptoms of GBS and shorten the recovery time.
The NINDS states that those with GBS are usually admitted and treated in a hospital’s intensive care unit because of possible complications of muscle weakness, problems that can affect any paralyzed person (such as pneumonia or bed sores), and the need for sophisticated medical equipment.
The WHO has listed recommendations for treatment and care, which include immunotherapy in the acute phase of the disease, supportive care including monitoring of breathing, heartbeat, and blood pressure, and rehabilitation services where muscle weakness continues after the acute phase of the illness.
